Testing high resolution SD ADC’s by using the noise transfer function

A new solution to improve the testability of high resolution SD Analogue to Digital Converters (SD ADC’s) using the quantizer input as test node is described. The theoretical basis for the technique is discussed and results from high level simulations for a 16 bit, 4th order, audio ADC are presented. The analysis demonstrates the potential to reduce the computational effort associated with test response analysis versus conventional techniques

A cybersecure P300-based brain-to-computer interface against noise-based and fake P300 cyberattacks

In a progressively interconnected world where the internet of things (IoT), ubiquitous computing, and artificial intelligence are leading to groundbreaking technology, cybersecurity remains an underdeveloped aspect. This is particularly alarming for brain-to-computer interfaces (BCIs), where hackers can threaten the user’s physical and psychological safety. In fact, standard algorithms currently employed in BCI systems are inadequate to deal with cyberattacks. In this paper, we propose a solution to improve the cybersecurity of BCI systems. As a case study, we focus on P300-based BCI systems using support vector machine (SVM) algorithms and EEG data. First, we verified that SVM algorithms are incapable of identifying hacking by simulating a set of cyberattacks using fake P300 signals and noise-based attacks. This was achieved by comparing the performance of several models when validated using real and hacked P300 datasets. Then, we implemented our solution to improve the cybersecurity of the system. The proposed solution is based on an EEG channel mixing approach to identify anomalies in the transmission channel due to hacking. Our study demonstrates that the proposed architecture can successfully identify 99.996% of simulated cyberattacks, implementing a dedicated counteraction that preserves most of BCI functions

Multiplexing pH and Temperature in a Molecular Biosensor

Robust and reliable measurements in electrochemical biosensing of molecules are crucial for personalized medicine. Electrochemical sensors based on cytochrome P450 can detect the large majority of drugs commonly used in pharmacological treatments. The same cytochrome can detect different substrates; each of them changes the electrochemical response of the enzyme in a specific manner. Our system exploits the measure of electrical potential to identify the drug type, while current measurements decode the drug concentration. Since potential and current are affected by pH and temperature, and since variations occur in the patient samples, we propose a novel design for multiplexing biosensing with pH and temperature control, which ensures more precise measurements for drugs identification and their quantification

A Novel Multi-Working Electrode Potentiostat for Electrochemical Detection of Metabolites

A novel single-chip and multiplexed read-out circuit for multi-electrode electrochemical sensors, in standard 0.18 μm UMC CMOS technology, is presented. The circuit is a part of a fully-integrated biochip (in design) for the detection of multiple metabolites. The proposed topology is based on the potentiostat approach, and it is devoted to detect currents within the range of 250 pA - 650 nA for an electrode active area of 0.25 mm2. The need of multi-metabolites monitoring asks for a system with multi-working electrodes. In the proposed configuration, switches select one working electrode at each clock phase, while the others are short-circuited to the reference one, in order to nullify the injected current inside the counter. Low noise and low energy topology (50μW at 1.5V of voltage supply) is employed for the control amplifier. The linearity of the proposed read-out circuit allows accuracy better than 0.1%

Spatio-Temporal Optimization of Perishable Goods’ Shelf Life by a Pro-Active WSN-Based Architecture

The waste in the perishable goods supply-chain has prompted many global organizations (e.g., FAO and WHO), to develop the Hazard Analysis and Critical Control Points (HACCP) protocol that ensures a high degree of food quality, minimizing the losses in all the stages of the farm-to-fork chain. It has been proven that good warehouse management practices improve the average life of perishable goods. The advances in wireless sensors network (WSN) technology offers the possibility of a “smart” storage organization. In this paper, a low cost reprogrammable WSN-based architecture for functional warehouse management is proposed. The management is based on the continuous monitoring of environmental parameters (i.e., temperature, light exposure and relative humidity), and on their combination to extract a spatial real-time prediction of the product shelf life. For each product, the quality decay is computed by using a 1st order kinetic Arrhenius model to the whole storage site area. It strives to identify, in a way compatible with the other products’ shelf lives, the position within the warehouse that maximizes the food expiration date. The shelf life computing and the “first-expired first-out” logistic problem are entrusted to a Raspberry Pi-based central unit, which manages a set of automated pallet transporters for the displacement of products, according to the computed shelf lives. The management unit supports several commercial light/temperature/humidity sensor solutions, implementing ZigBee, Bluetooth and HTTP-request interfaces. A proof of concept of the presented pro-active WSN-based architecture is also shown. Comparing the proposed monitoring system for the storage of e.g., agricultural products, with a typical one, the experimental results show an improvement of the expected expiration date of about 1.2 ± 0.5 days, for each pallet, when placed in a non-refrigerated environment. In order to stress the versatility of the WSN solution, a section is dedicated to the implemented system user interfaces that highlight detecting critical situations and allow timely automatic or human interventions, minimizing the latter

Field Programmable Gate Array-Embedded Platform for Dynamic Muscle Fiber Conduction Velocity Monitoring

This paper proposes a novel architecture of a wearable Field Programmable Gate Array (FPGA)-based platform to dynamically monitor Muscle Fiber Conduction Velocity (MFCV). The system uses a set of wireless sensors for the detection of muscular activation: four surface electromyography electrodes (EMGs) and two footswitches. The beginning of movement (trigger) is set by sensors (footswitches) detecting the feet position. The MFCV value extraction exploits an iterative algorithm, which compares two 1-bit digitized EMG signals. The EMG electrode positioning is ensured by a dedicated procedure. The architecture is implemented on FPGA board (Altera Cyclone V), which manages an external Bluetooth module for data transmission. The time spent for data elaboration is 63.5 ms ± 0.25 ms, matching real-time requirements. The FPGA-based MFCV estimator has been validated during regular walking and in the fatigue monitoring context. Six healthy subjects contributed to experimental validation. In the gait analysis, the subjects showed MFCV evaluation of about 7.6 m/s ± 0.36 m/s, i.e., <0.1 m/s, a typical value for healthy subjects. Furthermore, in agreement with current research methods in the field, in a fatigue evaluation context, the extracted data showed an MFCV descending trend with the increment of the muscular effort time (Rested: MFCV = 8.51 m/s; Tired: 4.60 m/s)

An Embedded Framework for Fully Autonomous Object Manipulation in Robotic-Empowered Assisted Living

Most of the humanoid social robots currently diffused are designed only for verbal and animated interactions with users, and despite being equipped with two upper arms for interactive animation, they lack object manipulation capabilities. In this paper, we propose the MONOCULAR (eMbeddable autONomous ObjeCt manipULAtion Routines) framework, which implements a set of routines to add manipulation functionalities to social robots by exploiting the functional data fusion of two RGB cameras and a 3D depth sensor placed in the head frame. The framework is designed to: (i) localize specific objects to be manipulated via RGB cameras; (ii) define the characteristics of the shelf on which they are placed; and (iii) autonomously adapt approach and manipulation routines to avoid collisions and maximize grabbing accuracy. To localize the item on the shelf, MONOCULAR exploits an embeddable version of the You Only Look Once (YOLO) object detector. The RGB camera outcomes are also used to estimate the height of the shelf using an edge-detecting algorithm. Based on the item’s position and the estimated shelf height, MONOCULAR is designed to select between two possible routines that dynamically optimize the approach and object manipulation parameters according to the real-time analysis of RGB and 3D sensor frames. These two routines are optimized for a central or lateral approach to objects on a shelf. The MONOCULAR procedures are designed to be fully automatic, intrinsically protecting sensitive users’ data and stored home or hospital maps. MONOCULAR was optimized for Pepper by SoftBank Robotics. To characterize the proposed system, a case study in which Pepper is used as a drug delivery operator is proposed. The case study is divided into: (i) pharmaceutical package search; (ii) object approach and manipulation; and (iii) delivery operations. Experimental data showed that object manipulation routines for laterally placed objects achieves a best grabbing success rate of 96%, while the routine for centrally placed objects can reach 97% for a wide range of different shelf heights. Finally, a proof of concept is proposed here to demonstrate the applicability of the MONOCULAR framework in a real-life scenario

A Digital Architecture for the Real-Time Tracking of Wearing off Phenomenon in Parkinson’s Disease

Levodopa administration is currently the most common treatment to alleviate Parkinson’s Disease (PD) symptoms. Nevertheless, prolonged use of Levodopa leads to a wearing-off (WO) phenomenon, causing symptoms to reappear. To build a personalized treatment plan aiming to manage PD and its symptoms effectively, there is a need for a technological system able to continuously and objectively assess the WO phenomenon during daily life. In this context, this paper proposes a WO tracker able to exploit neuromuscular data acquired by a dedicated wireless sensor network to discriminate between a Levodopa benefit phase and the reappearance of symptoms. The proposed architecture has been implemented on a heterogeneous computing platform, that statistically analyzes neural and muscular features to identify the best set of features to train the classifier model. Eight models among shallow and deep learning approaches are analyzed in terms of performance, timing and complexity metrics to identify the best inference engine. Experimental results on five subjects experiencing WO, showed that, in the best case, the proposed WO tracker can achieve an accuracy of ~84%, providing the inference in less than 41 ms. It is possible by employing a simple fully-connected neural network with 1 hidden layer and 32 units

Spatio-Temporal Optimization of Perishable Goods’ Shelf Life by a Pro-Active WSN-Based Architecture

The waste in the perishable goods supply-chain has prompted many global organizations (e.g., FAO and WHO), to develop the Hazard Analysis and Critical Control Points (HACCP) protocol that ensures a high degree of food quality, minimizing the losses in all the stages of the farm-to-fork chain. It has been proven that good warehouse management practices improve the average life of perishable goods. The advances in wireless sensors network (WSN) technology offers the possibility of a “smart” storage organization. In this paper, a low cost reprogrammable WSN-based architecture for functional warehouse management is proposed. The management is based on the continuous monitoring of environmental parameters (i.e., temperature, light exposure and relative humidity), and on their combination to extract a spatial real-time prediction of the product shelf life. For each product, the quality decay is computed by using a 1st order kinetic Arrhenius model to the whole storage site area. It strives to identify, in a way compatible with the other products’ shelf lives, the position within the warehouse that maximizes the food expiration date. The shelf life computing and the “first-expired first-out” logistic problem are entrusted to a Raspberry Pi-based central unit, which manages a set of automated pallet transporters for the displacement of products, according to the computed shelf lives. The management unit supports several commercial light/temperature/humidity sensor solutions, implementing ZigBee, Bluetooth and HTTP-request interfaces. A proof of concept of the presented pro-active WSN-based architecture is also shown. Comparing the proposed monitoring system for the storage of e.g., agricultural products, with a typical one, the experimental results show an improvement of the expected expiration date of about 1.2 ± 0.5 days, for each pallet, when placed in a non-refrigerated environment. In order to stress the versatility of the WSN solution, a section is dedicated to the implemented system user interfaces that highlight detecting critical situations and allow timely automatic or human interventions, minimizing the latter

FPGA Implementation of a Single Step MFCV Estimator Based on EMG in Diabetic Neuropathy

This paper details the design and the hardware implementation of a real-time diagnostic system based on FPGA for the muscle fibre conduction velocity estimation (MFCV). The MFCV is considered as a principal monitoring index for diabetic neuropathy (DPN), as well as in muscle fatigue assessment, to evaluate the muscle fibre status. The FPGA platform evaluates the MFCV during dynamic contractions (e.g., gait), by exploiting a multichannel sensing system composed of 4 wireless surface EMG electrodes, placed in pair on each leg. Raw data are digitized and made binary to create two bitstreams for each monitored limb. Then, a comparison between the two-bit streamed EMGs extracted from the same leg is carried out. The comparison, which allows extracting the MFCV, exploits a computationally light version of the cross-correlation method. The overall architecture implemented and validated on an Altera Cyclone V FPGA is HPS-free and exploits 22.5% ALMs, 10,874 ALUTs, 9.81% registers, 3.36% block memory, and <2.7% of the total wires available on the platform. The choice of FPGA as computing system lies in the possibility to determine resource utilization, related timing constraints for a future real-time ASIC implementation in wearable applications. From the actual muscle contraction during gait (cyclical starting point of the computing), the system spends about 316 ms to acquire useful data and 47.5 ms (on average) to process the signal and provide the output, dynamically dissipating 28.6 mW. The accuracy of the tool evaluation has been evaluated proving the repeatability of the measurements by in vivo test. In this context, 1250 contractions from each subject involved in a protocolled 10-meter walk have been acquired (n=10 subjects evaluated). On average, the same MFCV estimation has been extracted on 1184/1250 contractions (standard deviation of 11 contractions), reaching an accuracy of 94.7%. These estimations fully match the physiological value range reported in literature